Search results for " Copper complexes"
showing 4 items of 4 documents
Coordination polymers based on bridging cyanocarbanions and bis-tridentate p-phenylenediamine ligands
2017
Two new Cu(II) coordination polymeric neutral chains of formula [Cu 2 (1,4-tpbd)(μ-A) 2 (H 2 O) 2 ](A) 2 with A = tcnoet − ( 1 ) and tcnopr − ( 2 ) (1,4-tpbd = N,N,N′N′ -tetrakis(2-pyridylmethyl)benzene-1,4-diamine, tcnoet − = 1,1,3,3-tetracyano-2-ethoxypropenide and tcnopr − = 1,1,3,3-tetracyano-2-propoxypropenide) have been synthesized and characterized by infrared spectroscopy, X-ray diffraction and magnetic measurements. 1 and 2 show alternating chains where the 1,4-tpbd and the cyanocarbanion units (tcnoet − for 1 and tcnopr − for 2 ) alternate as bridging ligands. The molecular structure can be viewed as [Cu 2 (μ-tpbd)] 4+ dinuclear units (with Cu⋯Cu distances of 8.2233(3) for 1 …
Design, synthesis and biological evaluation of new anticancer drugs: FGFR inhibitors
2021
Fibroblast growth factor receptors (FGFRs) constitute a family of tyrosine kinases receptors (RTKs) that exert pivotal physiological functions in human embryonic and adult tissues. Hyperactivated FGFR signaling drives tumorigenesis in multiple cancer types, including lung and brain cancers. Great effort has been laid on the development of new compounds that specifically target the FGFR axis. However, cancer cell- based and microenvironmental resistance mechanisms against FGFR inhibitors often arise and are currently poorly understood. Furthermore, FGFR-targeted therapy often presents different side effects, e due to the broad biological spectrum of the FGFR signaling axis as well as to its …
A CI study of the CuCO and CuCO+ complexes
1987
MO CI calculations are carried out using an optimal space of valence virtual MOs obtained by means of a projection technique, as a linear combination of the AOs which are more occupied in the molecular Fock space. Localization of the occupied MOs and nonvalence virtual MOs is also achieved. The overall procedure is proven to be quite advantageous and well suited to obtain potential energy curves which keep the same physical meaning along the range of distances studied. Using a slightly better than double‐zeta quality basis set, a valence CAS‐CI, and selected CI wave function by the CIPSI algorithm have revealed a possible weak van der Waals interaction for the 2Σ+ state of CuCO, which remai…
Magnetic exchange interactions in the heteropoly complexes [M4(H2O)2(PW9O34)2]10− [M=Co(II) and Cu(II)]
1990
The magnetic properties of the heteropolyanions [M4(H2O)2(PW9O34)2]10− [M=Co(II) and Cu(II)] down to 4 K are reported. Their individual heteropoly molecules contain a rhomblike arrangement formed by four coplanar MO6 octahedra sharing edges. The magnetic properties support an intramolecular ferromagnetic exchange in the Co(II) tetramer, and antiferromagnetic exchange in the Cu(II) tetramer. These behaviors are discussed assuming anisotropic exchange in the Co(II) compound, and Heisenberg exchange in the Cu(II) compound. Carlos.Gomez@uv.es